Influences of low-protein diet on renal function and nutritional status in patients with stage 3/4 chronic kidney diseases
10.3760/cma.j.issn.1674-635X.2009.06.006
- VernacularTitle:低蛋白饮食对3/4期慢性肾脏病患者肾功能及营养状况的影响
- Author:
Chunhai SHAO
;
Yun ZHU
;
Jingfang LIU
;
Jun XUE
;
Fang TIAN
;
Junfeng LIU
- Publication Type:Journal Article
- Keywords:
chronic kidney disease;
nutritional status;
low-protein diet
- From:
Chinese Journal of Clinical Nutrition
2009;17(6):339-342
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the influences of low-protein diet on the renal function and nutritional status in patients with stage 3/4 chronic kidney diseases (CKD).Methods Totally 34 patients with stage 3/4 CKD were randomly divided into group A (protein intake:0.6 g·kg~(-1)·d~(-1);n=14) and B (protein intake:0.8 g·kg~(-1)·d~(-1);n=20).Anthropometric measurement and blood biochemical tests were performed,nutri-tional status was assessed,and 24-hour dietary recall survey was conducted before and after the treatment.Patients were followed up for 6 months.Results In group A,the creatinine level significantly decreased (P=0.010),while albumin level (P=0.042) and the intake of energy (P=0.018) and carbohydrate (P<0.001) signifi-cantly increased after the treatment In all the 34 patients,in group A and group B,the malnutrition rates were de-creased by 14.7%,7.2%,and 21.1% after nutritional intervention.Conclusion The low-protein diet (protein intake 0.6 g·kg~(-1)·d~(-1)),in which part of the staple food was replaced by wheat starch,can increase the in-takes of carbohydrate and energy and improve renal function and nutritional status in patients with stage 3/4 CKD.
