Hemodynamics of hepatic focal nodular hyperplasia with contrast-enhanced ultrasonography
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.1004-4477.2010.01.007
   		
        
        	
        		- VernacularTitle:肝局灶性结节性增生的超声造影血流动力学研究
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Wenping WANG
			        		
			        		;
		        		
		        		
		        		
			        		Peili FAN
			        		
			        		;
		        		
		        		
		        		
			        		Ruixue WEI
			        		
			        		;
		        		
		        		
		        		
			        		Hong DING
			        		
			        		;
		        		
		        		
		        		
			        		Beijian HUANG
			        		
			        		;
		        		
		        		
		        		
			        		Zhengbiao JI
			        		
			        		;
		        		
		        		
		        		
			        		Chaolun LI
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Ultrasonography;
			        		
			        		
			        		
				        		Microbubbles;
			        		
			        		
			        		
				        		Focal nodular hyperplasia
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Ultrasonography
	            		
	            		 2010;19(1):21-24
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective To investigate enhancement appearance of hepatic focal nodular hyperplasia(FNH) at real-time gray-scale contrast enhanced ultrasonography(CEUS),and evaluate the value of CEUS in the diagnosis of FNH. Methods Thirty-four patients (36 lesions) with histologically proved FNH were examined by ultrasonography. Appearance on conventional ultrasonography and the enhancement pattern on CEUS were investigated. Results Thirty-six lesions were mostly hypoechoic.39% (14/36) of lesions had peripheral hypoechogenic circle. Color Doppler flow imaging showed a asteroid-like or spoke-and-wheel pattern in 65% (20/ 31) of lesions.Three enhancement patterns were observed in the early arterial phase: whole-enhancement pattern (28%, 10/36), gushing-spring enhancement pattern (44%, 16/36), and spoke-and-wheel enhancement pattern (28%,10/36).The frequency of central scar on CEUS was 17% (6/36), and detection rate of central scar by CEUS compared with pathology was 40% (6/15).Regarding one of the features (gushing-spring enhancement, spoke-and-wheel enhancement and scar) as standard of FNH, the coincidence of CEUS in this group was 78% (28/ 36) ,which was significantly higher than that of conventional ultrasonography 28% (10/36).Conclusions CEUS can be as a important method for diagnosing FNH.