The value of diagnosing gastrointestinal dysfunction in critically ill children with criteria
10.3760/cma.j.issn.1673-4904.2010.06.003
- VernacularTitle:危重症患儿胃肠功能衰竭诊断指标价值的探讨
- Author:
Ni ZHANG
;
Fan WANG
;
Xiaonan XU
;
Baoquan ZHU
;
Qingli ZHANG
;
Guanjian LIU
- Publication Type:Journal Article
- Keywords:
Critical illness;
Gastrointestinal dysfunction;
D-lactate;
Intestinal fatty acid binding protein
- From:
Chinese Journal of Postgraduates of Medicine
2010;33(6):7-8
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the value of diagnosing gastrointestinal dysfunction in.critically ill children.Methods Seventy-six critically ill patients were reviewed,48 cases combined with gastrointestinal dysfunction.Plasma D-lactate,intestinal fatty acid binding protein(IFABP)of serum and urine were performed in all patients,detected the sensitivity and specificity,ealculated the area under the ROC curve (AUC).Results Plasma D-Iactate level≥9.63 mg/L had a sensitivity of 85.2%,specificity of 70.9%,and AUC of 0.822 for diagnosing gastrointestinal dysfunction.Serum IFABP level≥0.129μg/L had a sensitivity of 65.2%,specificity of 63.8%,and AUC of 0.744 for diagnosing gastrointestinal dysfunction.Urine IFABP ≥0.330μg/Lhad a sensitivity of 78.3%,specificity of 72.3%,and AUC of 0.820 for diagnosing gastrointestinal dysfunction.There was no significant difference in AUC between plasma and urine IFABP(P＞0.05),there was no significant difference in AUC between serum D-lactate and serum IFABP(P＞0.05).Conclusions Plasma D-Lactgte,serum and urine WABP may be useful markers as warning gastrointestinal dysfunction of critically ill children.Plasma D-lactate and urine IFABP level may be more sensitively,but they need to be further studied.
