Early-onset Childhood Sarcoidosis with Incidental Multiple Enchondromatosis.
10.3346/jkms.2012.27.1.96
- Author:
Jong Hwa LEE
1
;
Yeon Jung LIM
;
Seunghun LEE
;
Kyung Bin JOO
;
Yun Young CHOI
;
Chan Kum PARK
;
Young Ho LEE
Author Information
1. Department of Pediatrics, Wonkwang University Sanbon Medical Center, Gunpo, Korea.
- Publication Type:Case Reports ; Research Support, Non-U.S. Gov't
- Keywords:
Sarcoidosis;
Polyarthritis;
Enchondromatosis;
Nodule;
Childhood
- MeSH:
Administration, Oral;
Anti-Inflammatory Agents/therapeutic use;
Arthritis/complications;
Child, Preschool;
Diagnosis, Differential;
Enchondromatosis/*complications/*diagnosis/drug therapy/radiography;
Exanthema/etiology;
Female;
Humans;
Positron-Emission Tomography and Computed Tomography;
Prednisone/therapeutic use;
Sarcoidosis/*complications/*diagnosis/drug therapy/radiography;
Whole Body Imaging
- From:Journal of Korean Medical Science
2012;27(1):96-100
- CountryRepublic of Korea
- Language:English
-
Abstract:
The triad of rash, arthritis, and uveitis seems to be characteristic for early-onset childhood sarcoidosis. We describe an interesting case of early-onset childhood sarcoidosis coexisting enchondromatosis, which clinically masquerade as Langerhans cell histiocytosis. A 33 months old girl presented with skin rash, subcutaneous nodules with polyarthritis, and revealed the involvement of lymph nodes as well as spleen during work-up. She also presented with multiple osteolytic lesions which pathologically proven enchondromatosis. Oral prednisone was prescribed at 2 mg/kg/day for 2 months until when subcutaneous nodules and joint swellings almost disappeared, and then slowly tapered over a period of 5 months. We report an unusual case of early-onset childhood sarcoidosis presented with osteolytic bone lesions which were irrelevant to sarcoidosis.
