To observe the efficacy of early application of continuous venovenous hemofiltration in elderly patients with contrast-induced acute kidney injury
10.3760/cma.j.issn.0254-9026.2010.03.013
- VernacularTitle:早期连续性血液滤过治疗老年造影剂急性肾损伤患者的疗效观察
- Author:
Tongqiang LIU
;
Zhijian DING
;
Juanjuan LI
;
Xi FENG
;
Liangfeng ZHANG
;
Sufei GONG
- Publication Type:Journal Article
- Keywords:
Renal insufficiency,acute;
Hemofiltration;
Contrast media
- From:
Chinese Journal of Geriatrics
2010;29(3):222-225
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the efficacy of early application of continuous venovenous hemofiltration (CVVHF) in elderly patients with contrast-induced acute kidney injury (AKI) .Methods A total of 36 elderly inpatients with contrast-induced AKI were randomly divided into two groups:CVVHF group (n= 18) and routine treatment group (n = 18).The renal function, the incidences of contrast-induced nephropathy (CIN), in-hospital events (pulmonary edema, myocardial infarction and shock), temporary renal-replacement therapy and in-hospital mortality were observed.Results The incidence of CIN was higher in routine treatment group than in CVVHF group [88.9% (16/18) vs.16.7% (3/18), P<0.05].Temporary renal-replacement therapy was required in 13(72.2%) patients of routine treatment group and in 2(11.1%) patients of CVVHF group (P<0.05).The rate of in-hospital events was higher in routine treatment group than in CVVHF group [83.3%(15/18) vs.22.2% (4/18), P<0.01].In-hospital mortality rate was higher in routine treatment group than in CVVHF group [16.7%(3/18) vs.5.6%(1/18), P>0.05].Conclusions Early application of CVVHF in patients with contrast-induced AKI after percutaneous coronary intervention appears to be effective in preventing the deterioration of renal function, and it could improve in-hospital outcomes.
