Long-term efficacy of splenectomcy for patients with advanced shistosomiasis japonica
10.3760/cma.j.issn.1007-8118.2010.05.004
- VernacularTitle:切脾对晚期血吸虫病病人的远期影响
- Author:
Yiming WU
;
Wenlin WU
;
Xiaofei XU
;
Renye DING
;
Wenjun ZHU
;
Lizhang WANG
- Publication Type:Journal Article
- Keywords:
Shistosomiasis;
Splenectomy Long-term efficacy
- From:
Chinese Journal of Hepatobiliary Surgery
2010;16(5):333-335
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the long-term efficacy of splenectomy for patients with advanced shistosomiasis japonica.Methods Levels of WBC,RBC,PLT,EOS,ALT,ALP,GGT,A,TB,HA,LN,Ⅳ-C,PCⅢ,IGG,IGA,C3,C4,CD3,CD4,CD8,CD19 in periphetral venous blood were determined in 239 patients with advanced shistosomiasis.Meanwhile,the liver,gallbladder and spleen were examined with ultrasonography.Results The levels of WBC,PLT,EOS,ALT,ALP,IGG,IGA,LN,Ⅳ-C,CD19 increased in splenectomy group,the levels of A,TB,CD3,CD4,C3,C4 decreased in splenectomy group,while RBC,HA,PCⅢ,CD8 were not changed.Conclusion Splenectomy is a danger to hepatic function.Humoral immunity increases while cellular immunity decreases in splenectomy group.Splenectomy may aggravate the hepatic fibrosis in patients with advanced shistosomiasis.
