Timing of tracheal intubation impact on the therapeutic effect of acute severe organophosphate poisoning patients

VernacularTitle:气管插管时机对急性重度有机磷中毒治疗效果的影响
Author: Yingjie CHEN ; Yunli CHEN ; Xianren WU ; Linxi HUANG
Publication Type:Journal Article
Keywords: Poisoning; Insecticide,orgnaophosphorus; Ventilators,mechanical; Intubation,intratracheal
From: Chinese Journal of Primary Medicine and Pharmacy 2010;17(15):2067-2069
CountryChina
Language:Chinese
Abstract: Objective To evaluate timing of tracheal intubation impact on the therapeutic effect of acute severe organophosphate poisoning( ASOPP) patients. Methods Retrospectively analyze 82 ASOPP patients with respiratory failure ( RF). The patients were divided into timely tracheal intubation group(n = 42) and delay tracheal intubation group (n =40) ,and compare the therapeutic effect of these two groups. Results Compared with timely tracheal intubation patients and delay tracheal intubation patients,total time of mechanical ventilation,hospital day decreased significantly (P<0.01) ,cure rate increased significantly (P<0.01) ,but complications [intermediate myasthenia syndrome (IMS) .pulmonary infection,cardiac damage and so on] had no significant difference(P>0.05). Conclusion It was exact that the therapeutic effect of timely tracheal intubation on rescuing the ASOPP patients, and the best time to tracheal intubation was in RF early period.