Livin gene-new target for cancer therapy
10.3760/cma.j.issn.1673-4203.2010.11.018
- VernacularTitle:Livin基因-肿瘤治疗新靶点
- Author:
Haojie WEN
;
Jing MA
;
Jun SUI
;
Xiaojiang LI
- Publication Type:Journal Article
- Keywords:
Livin;
inhibitor of apoposis protein;
cancer therapy
- From:
International Journal of Surgery
2010;37(11):774-777
- CountryChina
- Language:Chinese
-
Abstract:
Livin is a new and important member of the inhibitor of apoptosis protein(IAPs)family.Livin is high expressed in most human tumor cells, involved in apoptosis inhibition and closely related with tumor development and progression.Studies found that through the down-regulation or inhibition of Livin expression and the induction specific antibodies of Livin could inhibi and kill tumor cells, which provided a new method for tumors'diagnosis, cell and gene targeted therapy.
