Roles of pericytes in blood-brain barrier
10.3760/cma.j.issn.1673-4165.2010.09.015
- VernacularTitle:周细胞在血脑屏障中的作用
- Author:
Weiwei QIN
;
Ruijuan XIU
;
Xiaorui SHI
- Publication Type:Journal Article
- Keywords:
Pericytes;
Blood-brain barrier;
Neovascularization,physiologic;
Endothelial cells
- From:
International Journal of Cerebrovascular Diseases
2010;18(9):711-715
- CountryChina
- Language:Chinese
-
Abstract:
Pericytes are a very important cellular constituent of the blood-brain barrier.They play a regulatory role in brain angiogenesis,endothelial cell tight junction formation,blood-brain barrier differentiation,microvascular dynamic motion and structural stability.Pericytes exhibit unique functional characteristics in some diseases,such as cerebrovascular disease,neurodegenerative disease,neuroimmune disease and traumatic brain injury.This article reviews the roles of pericytes in the blood-brain barrier.
