Endovascular embolization treatment for Hunt-Hess poor-grade intracranial aneurysms
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.1673-4904.2011.02.001
   		
        
        	
        		- VernacularTitle:Hunt-Hess高分级颅内动脉瘤的血管内栓塞治疗
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Bo ZENG
			        		
			        		;
		        		
		        		
		        		
			        		Xianghe LU
			        		
			        		;
		        		
		        		
		        		
			        		Zequn LI
			        		
			        		;
		        		
		        		
		        		
			        		Xianxi TAN
			        		
			        		;
		        		
		        		
		        		
			        		Ming ZHONG
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Intracranial aneurysm;
			        		
			        		
			        		
				        		Embolization,therapeutic;
			        		
			        		
			        		
				        		Early stage
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Postgraduates of Medicine
	            		
	            		 2011;34(2):1-3
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective To explore the clinical therapeutic efficacy and value of endovascular embolization treatment for Hunt-Hess poor-grade intracranial aneurysms. Methods Eighty-seven patients with Hunt-Hess grade Ⅳ - Ⅴ intracranial aneurysrns were treated with endovascular embolization from May 2001 to February 2010,77 patients were grade Ⅳ and 10 patients were grade Ⅴ. Outcomes were assessed by using the Glasgow outcome scale (GOS). Results Follow-up time was from 3 months to 9 years. The therapeutic efficacy was as following according to GOS: 25 patients were grade Ⅰ , 5 patients were grade Ⅱ , 9 patients were grade Ⅲ , 12 patients were grade Ⅳ ,and 36 patients were grade Ⅴ. There were 55.17%(48/87) favorable outcome rate and 28.74% (25/87) mortality rate in all patients. There were 61.70%(29/47) favorable outcome rate and 25.53%(12/47) mortality rate in early stage treatment patients (diseased within 3 d), otherwise there were 47.50% (19/40) favorable outcome rate and 32.50%(13/40) mortality rate in medium and late stage treatment patients (diseased 3 d or later). There were no statistically significance in favorable outcome rate and mortality rate between them (P > 0.05). All the patients were embolized successfully ,technical complications occurred in 8 patients, 10 patients were found angiographic evidence of vasospasm. Conclusions Endovascular embolization is an effective method for treating Hunt-Hess poorgrade intracranial aneurysms. Early stage treatment is a feasible option because it can improve prognosis by reducing rebleeding and vasospasm.