The diagnostic value of serum β-CTX and urinary CTX/CR in lung cancer with bone metastasis
10.3760/cma.j.issn.1671-7368.2011.01.026
- VernacularTitle:血清Ⅰ型胶原羧端肽和尿Ⅰ型胶原羧端肽/肌酐检测在肺癌骨转移监测中的价值
- Author:
Xiangyang LI
;
Lin CHEN
;
Yinggang ZHU
- Publication Type:Journal Article
- Keywords:
Lung neoplasms;
Neoplasm metastasis;
β-crosslaps of type Ⅰ collagen
- From:
Chinese Journal of General Practitioners
2011;10(1):60-61
- CountryChina
- Language:Chinese
-
Abstract:
The study included 24 patients of lung cancer with bone metastasis, 26 patients of lung cancer without bone metastasis and 27 healthy controls. The serum levels of β-crosslaps of type Ⅰ collagen (β-CTX), M-MID and urinary β-CTX/creatinine (CTX/CR) were measured by ELISA. Results showed that the serum levels of β-CTX and urinary CTX/CR in lung cancer patients with bone metastasis were significantly higher than those without bone metastasis (P ＜ 0. 01 ). The findings suggest that the measurement of serum β-CTX and urinary CTX/CR may indicate bone metastasis in lung cancer.
