Alkaloids from the leaves of Nauclea officinalis
- Author:
Long FAN
;
Chunlin FAN
;
Ying WANG
;
Xiaoqi ZHANG
;
Qingwen ZHANG
;
Junqing ZHANG
;
Wencai YE
- Publication Type:Journal Article
- From:
Acta Pharmaceutica Sinica
2010;45(6):747-51
- CountryChina
- Language:Chinese
-
Abstract:
To study chemical constituents of the leaves of Nauclea officinalis, eight alkaloids were isolated from 95% ethanol extract by various chromatographic methods. The structures were elucidated on the basis of spectroscopic data (IR, UV, ESI-MS, 1D and 2D NMR) and identified as naucleactonin C (1), strictosamide (2), vincosamide (3), pumiloside (4), angustoline (5), angustine (6), 18, 19-dihydroangustine (7) and naucleofficine D (8). Compound 1 is a new indole alkaloid. Compounds 6 and 7 were isolated from this plant for the first time.
