Endoscopic ultrasound guided fine needle aspiration in diagnosis of mediastinal lesions
- VernacularTitle:内镜超声引导下细针穿刺抽吸术在纵隔病变诊断中的应用
- Author:
Yueming ZHANG
;
Guiyu CHENG
;
Zhihui ZHANG
;
Ning Lü
;
Xiaoyan LI
;
Shuangmei ZUO
;
Liyan XUE
;
Lei ZHANG
;
Xiaognang NI
;
Shaoqing LAI
;
Shun HE
;
Guixiang YU
;
Fenghuan JU
;
Huaying XUN
;
Guiqi WANG
- Publication Type:Journal Article
- Keywords:
Endoscopic ultrasonograpby;
Biopsy,needle;
Medistinal diseases;
Lung neoplasms
- From:
Chinese Journal of Digestive Endoscopy
2008;25(12):621-625
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of endoscopic ultrasound guided fine-needle aspiration (EUS-FNA) in diagnosis of enlarged mediastinal lymph nodes (LNs), mediastinal occupying lesion of unknown origin, as well as in N-staging for lung cancer. Methods EUS-FNA was performed via esophagus with a 22-gange needle in 61 patients, followed by pathological and cytological examinations. Results The positive diagnosis rate of EUS-FNA was 93.4% (57/61), and the cytological and pathological diagnostic accuracy were 85.2% (52/61) and 83.6% (51/61), respectively. Of 61 patients, 26 were suspected as having lung cancer with mediastinal lymph nodes metastasis, but the bronchoscopy failed to confirm the diag-nosis. EUS-FNA diagnosed lung cancer in 21 and benign lesion in 5. Of 22 patients with mediastinal occupying lesions of unknown origin, 19 (86.4%) were diagnosed by EUS-FNA. Of 7 patients with malignant tumor history and enlarged mediastinal lymph nodes, EUS-FNA confirmed mediastinal metastasis in 6 (85.7%). Six cases of lung cancer with suspected mediastinal lymph nodes metastasis were confirmed by EUS-FNA and the corresponding therapy regimen was modified. No complications related to EUS-FNA procedure occurred. Conclusion EUS-FNA is a safe and effective method for diagnosis of enlarged medistinal LNs, mediastinal lesion of unkown origin and N-stage of lung cancer.
