Application of hIL-24 gene in combination therapies of tumors
10.3760/cma.j.issn.1006-9801.2009.05.028
- VernacularTitle:人类白细胞介素-24基因在肿瘤联合治疗中的应用
- Author:
Peixia YU
;
Guiqin WANG
- Publication Type:Journal Article
- Keywords:
Interleukins;
Genes;
Neoplasms;
Therapy;
Therapeutic uses
- From:
Cancer Research and Clinic
2009;21(5):358-360
- CountryChina
- Language:Chinese
-
Abstract:
The human interleukin-24 gene (hIL-24),alse referred to as melanoma differentiation associated gene-7 (MDA-7), is a novel cancer-selective apoptosis-inducing eytokine gene with broadspectrum antitumor activity. Multiple data have demonstrated that treatment of tumors with a combination of IL-24 and other strategies such as drug therapy, radiation, dual gene therapy and so on, caused synergistic antitumor effects. These results will provide a impetus for further combination therapy in various tumors.
