Percutaneous endoscopic gastrostomy in long-term coma patients at different phases: a report from neurosurgical department
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.1007-5232.2010.05.006
   		
        
        	
        		- VernacularTitle:不同时期经皮内镜胃造瘘术在神经外科长期昏迷患者中的应用
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Haisong XU
			        		
			        		;
		        		
		        		
		        		
			        		Qizhou JIANG
			        		
			        		;
		        		
		        		
		        		
			        		Weimin WANG
			        		
			        		;
		        		
		        		
		        		
			        		Guomin XIAO
			        		
			        		;
		        		
		        		
		        		
			        		Jun CHENG
			        		
			        		;
		        		
		        		
		        		
			        		Jianyue WU
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Time factors;
			        		
			        		
			        		
				        		Endoscopes;
			        		
			        		
			        		
				        		Intubation,nasogastric;
			        		
			        		
			        		
				        		Coma
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Digestive Endoscopy
	            		
	            		 2010;27(5):248-251
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective To evaluate percutaneous endoscopic gastrostomy (PEC) in long-term coma patients at different phases who received trans-nasal feeding in Department of Neurosurgery. Methods A total of 51 patients who received trans-nasal feeding because of long-term coma were randomly divided into 2 groups to undergo PEG at 25-39 days after coma (n =24) or at 40-60 days (n = 27) , respectively. The rates of upper gastrointestinal bleeding, average episodes of bleeding, average hemostatic time, the rates of aspiration and aspiration pneumonia were compared between the 2 groups. Results The rates of upper gastrointestinal bleeding, aspiration and aspiration pneumonia in post-PEG patients were significantly lower than those in pre-PEG patients (P < 0.05). Before the procedure of PEG, the rates of upper gastrointestinal hemorrhage,average episodes of bleeding, rates of aspiration and aspiration pneumonia in 25-39-day group were significantly lower than those in 40-60-day group (P < 0.05). There was no significant difference between 2 groups, in regarding of either hemostatic time, or rates of upper gastrointestinal bleeding, aspiration and aspiration pneumonia after PEG (P > 0. 05). Conclusion PEG may decrease the rates of upper gastrointestinal bleeding, aspiration and aspiration pneumonia in neurosurgical patients receiving trans-nasal feeding because of long-term coma. PEG is preferably performed on 25-39 days of onset to 40-60 days. If there is no contraindication, 25-39 days after coma is likely to be the optimal time for PEG.