The Efficacy of Kampo Medicine as a Prophylactic Way to Influenza Virus Type A Infection in an Epidemic Season of 2004/05
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3937/kampomed.58.847
   		
        
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Hisayuki HIRAIWA
			        		
			        		;
		        		
		        		
		        		
			        		Yoko OHTA
			        		
			        		;
		        		
		        		
		        		
			        		Rika HIRAIWA
			        		
			        		;
		        		
		        		
		        		
			        		Sachiko KANATSU
			        		
			        		;
		        		
		        		
		        		
			        		Yasushi HIROSE
			        		
			        		;
		        		
		        		
		        		
			        		Shinya DATE
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Hozai (prescriptions for recovery of the kyo (the asthenic state));
			        		
			        		
			        		
				        		influenza;
			        		
			        		
			        		
				        		mass infection;
			        		
			        		
			        		
				        		prevention;
			        		
			        		
			        		
				        		social welfare institution handicapped persons
			        		
			        		
	        			
        			
        		
 
        	
            
            	- MeSH:
            	
	        			
	        				
	        				
				        		
					        		Medicine, Kampo;
				        		
			        		
				        		
					        		Seasons;
				        		
			        		
				        		
					        		Infection as complication of medical care;
				        		
			        		
				        		
					        		Influenza;
				        		
			        		
				        		
					        		Prophylactic
				        		
			        		
	        			
	        			
            	
            	
 
            
            
            	- From:Kampo Medicine
	            		
	            		 2007;58(5):847-852
	            	
            	
 
            
            
            	- CountryJapan
 
            
            
            	- Language:Japanese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	We retrospectively investigated the prevalence of influenza virus type A infection and the efficacy of Kampo medicine as a prophylactic for handicapped residents at our social welfare institution, during the 2004/5 flu season. Upon studying a nationwide surveillance report for said season, we supposed that it had been difficult to prevent mass infection at our welfare institution with the usual preventive methods, because type B had prevailed for most of the season, and because of the differing type A (AH 3) antigenicity which prevailed late-season, for which there were no type A vaccines.43 of 90 (47.8%) residents given flu vaccinations twice, and 25 of 110 (22.7%) of staff members given flu vaccinations once contracted type A influenza between March and May of 2005. Interestingly, residents who had been administered Hozai for either short-term health problems or chronic disease, demonstrated a low influenza prevalence, there being a statistically significant difference (p<0.05) between our “Hozai” and “non-Hozai” groups. Furthermore Juzentaihoto, known to enhance immune function, seemed beneficial because of its low associated morbidity rate, and only 2 of 8 residents administered it contracted flu. No difference was observed, however, between generalized “Kampo treatment” and “non-Kampo treatment” groups.We consider that certain Kampo medicines may be useful for the prevention of influenza infection, in institutionalized handicapped residents with short-term health problems. Immunological enhancements, and the influence of Hozai are discussed here.