Effects of Oral Administration of CoenzymeQ10 to Nonenal in Skin Gas of Elderly Women
	    		
	    			
	    			
		        		
			        		
		        		
			        
		   		
		   		
		   			
		   		
	    	
    	 
    	10.1625/jcam.14.17
   		
        
        	
        		- VernacularTitle:コエンザイムQ10摂取が高齢女性の皮膚ガス中の加齢臭成分ノネナールに与える影響
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Masako KATSUYAMA
			        		
			        		;
		        		
		        		
		        		
			        		Yumiko HISADA
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		coenzymeQ10;
			        		
			        		
			        		
				        		skin gas;
			        		
			        		
			        		
				        		nonenal;
			        		
			        		
			        		
				        		nonanal;
			        		
			        		
			        		
				        		body odor
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:Japanese Journal of Complementary and Alternative Medicine
	            		
	            		 2017;14(1):17-22
	            	
            	
 
            
            
            	- CountryJapan
 
            
            
            	- Language:Japanese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	To evaluate the impact of coenzyme Q10 (CoQ10) intake on body odor, two studies that focused on 2-nonenal contained in the gases emanated from the skin were conducted. The first study targeted 20 healthy women aged 65–74 years in a placebo-controlled cross-comparison study. Subjects were divided into two groups using blood CoQ10 concentration as an index, with ubiquinol (QH) or placebos administered every 4 weeks (5-week washout). On measuring concentrations of CoQ10 in blood and 2-nonenal in skin gas before and after continuous use, CoQ10 level of QH intake group increased significantly, whereas 2-nonenal level reduced significantly. In the second study, 24 healthy women aged 65–74 years were divided into four groups. QH, ubiquinone, vitamin E and placebos were administered in 4 weeks, and each concentrations of 2-nonenal in skin gas were measured. QH and ubiquinone reduced 2-nonenal in skin gas; however, changes in vitamin E were not observed. Therefore, CoQ10 intake reduced 2-nonenal emanation from the body.