Two Cases of Persistent Hiccups with a Previous History of Cerebral Hemorrhage, Successfully Treated with Hangekobokuto Extract
	    		
	    			
	    			
		        		
			        		
		        		
			        
		   		
		   		
		   			
		   		
	    	
    	 
    	10.3937/kampomed.67.150
   		
        
        	
        		- VernacularTitle:半夏厚朴湯が著効した脳出血既往のある持続性吃逆の2症例
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yoshinao HARADA
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		hiccups;
			        		
			        		
			        		
				        		cerebral hemorrhage;
			        		
			        		
			        		
				        		hangekobokuto;
			        		
			        		
			        		
				        		shakuyakukanzoto
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:Kampo Medicine
	            		
	            		 2016;67(2):150-154
	            	
            	
 
            
            
            	- CountryJapan
 
            
            
            	- Language:Japanese
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	We report our experience with two patients who had a previous history of cerebral hemorrhage and presented with persistent hiccups. Hangekobokuto was found to be effective in these patients. Case 1 was a 49-year-old man with a history of cerebral hemorrhage who experienced persistent hiccups as a result of pulmonary aspiration that occurred while he was admitted to the hospital for heat stroke. Abdominal palpation revealed epigastric resistance and tenderness. Metoclopramide and shakuyakukanzoto were administered without any amelioration of the symptoms, but the symptoms disappeared 1 hr after changing the drug regimen to hangekobokuto. Case 2 was a 64-year-old man who experienced persistent hiccups 28 days after suffering a cerebral hemorrhage. Abdominal palpation revealed epigastric resistance and tenderness and a lack of resistance at the lower abdomen. Because a regimen of metoclopramide and shakuyakukanzoto was similarly ineffective, we changed the drug regimen to hangekobokuto, and the symptoms subsequently disappeared 7 hr after administration. The symptoms did not recur in either patient following treatment. Hangekobokuto can be effective in cases of persistent hiccups is worth considering as a treatment option.