Liver Injury Related to Kampo Medicine:Diagnosis, Incidence, and Clinical Features
10.3937/kampomed.66.342
- VernacularTitle:漢方薬による肝障害
- Author:
Naoki MANTANI
- Publication Type:Journal Article
- Keywords:
drug-induced liver injury;
Kampo medicine;
diagnosis;
incidence;
clinical feature
- From:Kampo Medicine
2015;66(4):342-351
- CountryJapan
- Language:Japanese
-
Abstract:
To diagnose liver injury related to Kampo medicine accurately is not easy. Lymphocyte transformation tests are likely to give a false positive for Kampo medicine. Diagnostic criteria with a scoring system provide low specificity for the diagnosis of Kampo-related liver injury. This article intends to outline the problems with diagnosing Kampo-induced hepatic injury, and to review previous studies to shed light on its incidence and clinical features. Kampo-related liver injury incidence was 0.1% or less, and that related to Scutellariae Radix was 0.5-1.0% in the literature. The symptoms, types, and recovery periods were similar to those for western drug-related liver injuries.
