Detection of HER-2 Protein and DNA Amplification in Breast, Stomach and Colon Cancers

VernacularTitle:当院におけるHER-2の検出状況
Author: Satoshi IKEDA ; Chigusa NAGATA ; Keiko SUZUKI
Publication Type:Journal Article
From:Journal of the Japanese Association of Rural Medicine 2014;63(2):99-104
CountryJapan
Language:Japanese
Abstract: 　　We investigated the detection situation of the HER-2 examination that was performed to investigate the adaptation of the molecular targeted medicine trastuzumab for mammary and gastric cancers. The HER-2 positive rate was higher in biopsy specimens than in surgical specimen. In gastric cancer, the positive rate was significantly high when it was of the papillary type, histologically. In comparison with mammary cancer, the percentage of FISH positive was high in 2＋ cases. In addition, as the results of trial investigation showed, HER-2 positive cases ware few in colon cancer.