Biochemical and immunohistochemical changes in gastrocnemius muscle of rats fed low protein diet following electrical stimulation.
- VernacularTitle:電気刺激後のラットひ腹筋における生化学的，形態学的変化 低たん白食の影響
- Author:
TOSHIMI MIZUNUMA
;
KENTARO SAKAI
;
NORIKO KAWAHITO
;
HIROTOSHI IWASHINA
;
SHIGERU YAMAMOTO
;
YUKARI KAWANO
;
SACHINOBU MANABE
;
KAZUE NAGATA-KUNO
- Publication Type:Journal Article
- Keywords:
electrical stimulation;
gastrocnemius muscle;
low protein diet
- From:Japanese Journal of Physical Fitness and Sports Medicine
1997;46(5):471-478
- CountryJapan
- Language:Japanese
-
Abstract:
We investigated biochemical and morphological changes in electrically stimulated gastrocnemius muscle of rats fed normal (20% casein) and low-protein (5% casein) diets. Tissue weight and protein content per tissue weight of gastrocnemius muscle were significantly decreased in rats fed 5% casein diet than in rats fed 20% casein diet. Immunohistochemically, cathepsin B antigen was detected in inflammatory cells, and injured sites determined immunological intensity of anti-cathepsin B were lower in 5% casein diet group than 20% casein diet group. Electron microscopically, there was delayed repairment of muscle components (sarcometric units) in 5% casein diet as compared with that in 20% casein diet group.
