Aortic Root Replacement for Destructive Aortic Valve Endocarditis or Aortitis
	    		
	    			
	    			
		        		
			        		
		        		
			        
		   		
		   		
		   			
		   		
	    	
    	 
    	10.4326/jjcvs.36.315
   		
        
        	
        		- VernacularTitle:大動脈弁輪破壊を伴った感染性心内膜炎,大動脈炎に対する大動脈基部再建術
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Kenji Okada
			        		
			        		;
		        		
		        		
		        		
			        		Hiroshi Tanaka
			        		
			        		;
		        		
		        		
		        		
			        		Naoto Morimoto
			        		
			        		;
		        		
		        		
		        		
			        		Hiroshi Munakata
			        		
			        		;
		        		
		        		
		        		
			        		Mitsuru Asano
			        		
			        		;
		        		
		        		
		        		
			        		Masamichi Matsumori
			        		
			        		;
		        		
		        		
		        		
			        		Atsushi Kitagawa
			        		
			        		;
		        		
		        		
		        		
			        		Yujiro Kawanishi
			        		
			        		;
		        		
		        		
		        		
			        		Keitaro Nakagiri
			        		
			        		;
		        		
		        		
		        		
			        		Yutaka Okita
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
            
            
            	- From:Japanese Journal of Cardiovascular Surgery
	            		
	            		 2007;36(6):315-320
	            	
            	
 
            
            
            	- CountryJapan
 
            
            
            	- Language:Japanese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Destructive aortic valve endocarditis or poor controlled aortitis cause the development of left ventricular-aortic discontinuity. We reported our experience with aortic root replacement for cases of severe aortic annular destruction. Between 1999 and 2006, 9 patients with severe aortic annular destruction underwent aortic root replacement at our institute. There were 8 men and one women with a mean age of 55 years. Seven patients were in New York Heart Association functional class III. Four of 9 patients had native valve endocarditis, 4 had prosthetic valve endocarditis (previous aortic valve replacements in 2, aortic root replacements in 2) and one had active aortitis with a detached mechanical valve. Radical debridement of the infected cavity and necrotic tissue was performed in all cases, followed by reconstruction of the aortic annulus using autologous or xenogenic pericardium in 3 cases. Antibiotic-saturated fibrin glue was applied to the cavity. Aortic root replacement was achieved with a pulmonary autograft (Ross procedure) in 4 and stentless aortic root xenograft in 4. One patient who had advanced liver cirrhosis underwent aortic valve replacement with a stentless xenograft by subcoronary implantation method. No mortality was observed during hospitalization and follow-up. Reoperation within 5 years was not necessary in 66.7% of the patients. Excellent outcome can be achieved by radical exclusion of the abscess cavity and viable pulmonary autograft or stentless aortic root xenograft in patients with severe aortic annular destruction.