Double-pump implantation chemotherapy for hepatic metastasis from colorectal cancer.
- Author:
Jianmiao HE
1
;
Yongdong PU
;
Zhidong ZHU
;
Zhiyu CAO
;
Bo YANG
;
Liguo DONG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Colorectal Neoplasms; drug therapy; pathology; Drug Therapy; methods; Female; Hepatic Artery; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Infusions, Intravenous; Liver Neoplasms; drug therapy; secondary; Male; Middle Aged; Portal Vein; Therapeutics
- From: Chinese Journal of Oncology 2002;24(2):167-169
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the value of infusion chemotherapy by pump implantation via hepatic artery or portal vein or both (double-pump chemotherapy, DPC) for hepatic metastasis from colorectal cancer.
METHODSThirty patients with hepatic metastasis from colorectal cancer were divided into three groups: 1. Group I-DPC (12 patients). 2. Group II-hepatic artery implantation chemotherapy (10 patients) and 3. Group III-portal vein implantation chemotherapy (8 patients).
RESULTSResponse rate was 66.7% in group I, 60% in group II and 37.5% in group III. The 0.5-, 1-, 2-year survival rates were 100.0%, 75.0%, 41.7% in group I, 90.0%, 60.0%, 30.0% in group II and 87.5%, 50.0%, 25.0% in group III.
CONCLUSIONDouble pump implantation chemotherapy is effective in treating hepatic metastasis from colorectal cancer. It is better than hepatic artery or portal vein pump-implantation chemotherapy alone.
