A new lignan from stem bark of Syringa pinnatifolia.

Author: Rui-Feng BAI ¹ ; Guo-Zhu SU ¹ ; Xiao FENG ¹ ; Rui-Fei ZHANG ¹ ; Xu YIN ¹ ; Yun-Yun YE ¹ ; Su-Yi-le CHEN ² ; Peng-Fei TU ¹ ; Xing-Yun CHAI ¹
Author Information

1. Modern Research Center for Traditional Chinese Medicine, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China.
2. Alashan League Mongolian Medicine Hospital, Alashan League 750300, China.
Publication Type:Journal Article
Keywords: Mongolian folk medicine; Syringa pinnatifolia; Z-pinnatifolin A
From: China Journal of Chinese Materia Medica 2017;42(7):1229-1233
CountryChina
Language:Chinese
Abstract: One new lignan, named Z-pinnatifolin A, along with ten known analogues, were isolated from the stem bark of Syringa pinnatifolia by various chromatographic methods. Their structures were extensively determined on basis of MS and NMR spectroscopic data analyses, and comparison with those in literature. Among them, compounds 3,4, and 8-11 were isolated from this genus for the first time, and 5-7 were isolated from the specie for the first time. Compound 1 showed a moderate inhibition on NO production in BV-2 cells. The present study provides a preliminary data for clarification of bioactive ingredients of S.pinnatifolia with anti-myocardial ischemic effect.