Antimicrobial resistance of 36 strains of Helicobacter pylori in adolescents.
- Author:
Lie-Ping HUANG
1
,
2
;
Man-Li ZHUANG
;
Cheng-Ping GU
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Amoxicillin; pharmacology; Anti-Infective Agents; pharmacology; Child; Clarithromycin; pharmacology; Drug Resistance, Bacterial; Female; Gastroscopy; Helicobacter pylori; drug effects; Humans; Levofloxacin; Male; Metronidazole; pharmacology; Microbial Sensitivity Tests; Ofloxacin; pharmacology
- From: Chinese Journal of Contemporary Pediatrics 2009;11(3):210-212
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the resistance of Helicobacter pylori (H. pylori) to antimicrobial agents in adolescents.
METHODSOne hundred and eight adolescents (6-18 years old) underwent a gastroscopy examination. H. pylori strains were isolated from gastric mucosa. Antimicrobial susceptibility testing was performed by means of Kirby-Baner.
RESULTSThirty-six H. pylori strains were identified. The resistant rate of H. pylori strains to clarithromycin, fruranzolidone and amoxicillin was 8.3%, 16.7% and 33.3%, respectively. H. pylori strains showed a high resistance to metronidazole (94.4%), while no strain was resistant to gentamicin and levofloxacin.
CONCLUSIONSThe H. pylori strains from the adolescents in Zhejiang showed a high resistance to metronidazole and amoxicillin but a low resistance to clarithromycin and fruranzolidone. All of H. pylori strains were susceptive to gentamicin and levofloxacin.
