Clinical analysis of proteinuria and glomerular lesions in Henoch-Schönlein purpura nephritis of adults.
- Author:
Dong-yan LIU
1
;
Yu-bing WEN
;
Hang LI
;
Xue-wang LI
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Female; Glomerulonephritis, IGA; diagnosis; etiology; Humans; Immunoglobulin A; blood; Immunoglobulin G; blood; Immunoglobulin M; blood; Kidney Glomerulus; pathology; Kidney Tubules; pathology; Male; Middle Aged; Nephritis; diagnosis; etiology; Proteinuria; etiology; urine; Purpura, Schoenlein-Henoch; complications; pathology; Retrospective Studies
- From: Acta Academiae Medicinae Sinicae 2005;27(2):237-240
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo analyze the characteristics of proteinuria and glomerular lesions in Henoch-Schönlein purpura nephritis (HSPN) of adults.
METHODSThe pathologic results and clinical data of 103 HSPN patients were analyzed.
RESULTSPatients with mild or moderate proteinuria accounted for 40.8% and 37.9%, respectively. Patients with nephropathic proteinuria accounted for about 21.4%. Severer proteinuria resulted in higher blood pressure and increased cholesterol, and albumin decreased gradually (P < 0.01); meanwhile, total glomerular lesion, tubulointerstitial lesion, and vascular lesion also became severer (P < 0.01).
CONCLUSIONProteinuria may indirectly reflect the severity of glomerular lesions in HSPN of adults.
