Laparoscopy and digital subtraction angiography in the treatment of severe acute pancreatitis.
- Author:
Kai-yun CHEN
1
,
2
;
Guo-an XIANG
;
Han-ning WANG
;
Peng GAO
;
Fang-lian XIAO
Author Information
- Publication Type:Journal Article
- MeSH: APACHE; Adult; Aged; Angiography, Digital Subtraction; methods; Combined Modality Therapy; Drug Therapy; methods; Female; Hospital Mortality; Humans; Interleukin-10; blood; Interleukin-1beta; blood; Laparoscopy; methods; Male; Middle Aged; Pancreatitis, Acute Necrotizing; diagnosis; mortality; therapy; Prognosis; Treatment Outcome; Tumor Necrosis Factor-alpha; blood
- From: Chinese Journal of Surgery 2007;45(11):750-752
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the effect of laparoscopy and digital subtraction angiography in the treatment of severe acute pancreatitis (SAP).
METHODSSeventy-five SAP patients were randomly divided into tow groups: (1) Conventional treatment group (group A, n = 35); (2) Conventional treatment combined with laparoscopy and digital subtraction angiography treatment group (group B, n = 40). The clinical parameters and treatment results in the 2 groups were compared.
RESULTSAfter treatment, APACHE II score in group B was significantly lower than that in group A (P < 0.05). The functions of liver, renal and lung were recovered (P < 0.05, respectively), levels of serum TNF-alpha and IL-1 beta were significantly lower, but IL-10 significantly elevated (P < 0.05), the CT SPN was much lower (P < 0.05); rate of organ failure significantly decreased (P < 0.01), the successful rate of organ failure treatment was increased (P < 0.05); the in hospital mortality decreased (all P < 0.05).
CONCLUSIONSLaparoscopy and digital subtraction angiography in combination with conventional treatment for SAP significantly improves the outcome and decrease the mortality of SAP.
