Considerations for submucosal midazolam administration in combination with oral and inhaled medications for sedation of pediatric dental patients.
10.17245/jdapm.2015.15.2.47
- Author:
Kwangwoo BAEK
1
Author Information
1. Department of Dentistry, Ajou University School of Medicine, Korea. pedobaek@nate.com
- Publication Type:Review
- Keywords:
Benzodiazepine;
Conscious sedation;
Midazolam;
Pediatric dentistry
- MeSH:
Amnesia;
Anxiety;
Benzodiazepines;
Chloral Hydrate;
Conscious Sedation;
Consciousness Disorders;
Deep Sedation;
Depression;
Humans;
Hydroxyzine;
Hypnotics and Sedatives;
Midazolam*;
Pediatric Dentistry;
Physical Stimulation;
Postoperative Nausea and Vomiting
- From:Journal of Dental Anesthesia and Pain Medicine
2015;15(2):47-52
- CountryRepublic of Korea
- Language:English
-
Abstract:
Sedation allows patients to maintain their airway independently and respond appropriately to physical stimulation and verbal command while maintaining a minimum depressed level of consciousness. Drugs commonly used for sedation of pediatric dental patients include a combination of chloral hydrate, hydroxyzine, and nitrous oxide-oxygen. Midazolam is a benzodiazepine and currently one of the most commonly used intravenous sedative agents. It can be easily titrated to provide a wide range of sedation, from conscious sedation to deep sedation, and exhibits a wide safety margin without severe respiratory and circulatory depression. At an appropriate dose, it also decreases patient anxiety and induces amnesia. We found that the submucosal administration of midazolam combined with chloral hydrate provided increased sedative effects and decreased the postoperative vomiting response compared with conventional chloral hydrate administration, with no significant difference in physiological responses. The depth of sedation can be titrated using this technique.
