Studies on chemical constituents of Clerodendrum bungei.
10.19540/j.cnki.cjcmm.2017.0214
- Author:
Gui-Jie ZHANG
1
;
Lu-Mei DAI
2
;
Bin ZHANG
2
;
Yong-Li ZHANG
1
;
Heng-Shan WANG
2
;
Dong LIANG
2
Author Information
1. College of Pharmacy, Guilin Medical University, Guilin 541004, China.
2. State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin 541004, China.
- Publication Type:Journal Article
- Keywords:
Clerodendrum bungei;
Verbenaceae;
chemical constituents;
diterpenoids
- From:
China Journal of Chinese Materia Medica
2017;42(24):4788-4793
- CountryChina
- Language:Chinese
-
Abstract:
Ten compounds were isolated from the 95% aqueous EtOH extract of Clerodendrum bungei by a combination of various chromatographic techniques including column chromatography over silica gel, Sephadex LH-20, MCI, ODS, and semi-preparative HPLC. Their structures were elucidated as 11,12,16S-trihydroxy-7-oxo-17(15→16),18(4→3)-diabeo-abieta-3,8,11,13-tetraen-18-oic acid (1), 12S*,13R*-dihydroxy-9-oxo-octadeca-10(E)-enoic acid (2), clerodenoside A (3), trichotomoside (4), glycosmisic acid (5), 4'-O-methylscutellarein (6), neroplomacrol (7), butylitaconic acid (8), hexylitaconic acid (9), p-hydroxybenzonic acid (10) by their physicochemical properties and spectroscopic data. Compounds 1 and 2 are new natural products, while compounds 7-10 were obtained from the genus Clerodendrum for the first time, and compounds 3, 5, 6 were isolated from this plant for the first time.
