Central pontine myelinolysis: a rare presentation secondary to hyperglycaemia.
- Author:
Monica SAINI
1
,
2
;
Marlie Jane MAMAUAG
;
Rajinder SINGH
Author Information
1. Department of Medicine, Changi General Hospital, 2 Simei Street 3, Singapore
2. sainimmm@gmail.com.
- Publication Type:Case Reports
- MeSH:
Diagnosis, Differential;
Female;
Humans;
Hyperglycemia;
complications;
Magnetic Resonance Imaging;
Middle Aged;
Myelinolysis, Central Pontine;
diagnosis;
etiology;
Tomography, X-Ray Computed
- From:Singapore medical journal
2015;56(4):e71-3
- CountrySingapore
- Language:English
-
Abstract:
Central pontine myelinolysis (CPM) is classically described as a demyelinating condition that results from the rapid correction of hyponatraemia. CPM has also been reported to arise from hyperglycaemia in association with concomitant acidosis, hypernatraemia and hyperosmolar syndrome. Herein, we report a rare presentation of CPM, which was purely secondary to hyperosmolar hyperglycaemia. The patient presented with ataxia and pseudobulbar affect, which evolved subacutely over a duration of two weeks. It is important to note that, in addition to acute changes in osmolality, a subacute shift secondary to hyperglycaemia may also lead to CPM.
