Epidemiological survey of high-risk human papillomavirus among 2501 woman.
- Author:
Jing-Na CHEN
1
,
2
;
Li-Dan CHEN
;
Wei-Yun ZHANG
;
Yong-Quan YANG
;
Rong-Zhi TANG
;
Zhao-Hui SUN
;
Lin-Hai LI
Author Information
- Publication Type:Journal Article
- MeSH: China; epidemiology; Female; Genotype; Humans; Papillomaviridae; classification; isolation & purification; Papillomavirus Infections; epidemiology; virology; Prevalence; Real-Time Polymerase Chain Reaction; Risk Factors; Uterine Cervical Neoplasms; virology
- From: Journal of Southern Medical University 2015;35(10):1487-1491
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo survey the prevalence of high-risk human papillomavirus (HPV) in woman in Guangzhou during the period from 2013 to 2014.
METHODSA total of 2501 women in Guangzhou seeking medical attention in our hospital underwent high-risk HPV genotype screening of cervical specimens using real-time PCR.
RESULTSThe prevalence of high-risk HPV infection among the women was 14.85% (146/983) in the year 2013, similar to the rate of 14.56% (221/1518) in 2014 (Χ(2)=0.041, P=0.839); no significant differences were found in the high-risk HPV infection rates between different age groups in either 2013 (Χ(2)=2.916, P=0.572) or 2014 (Χ(2)=6.494, P=0.165). The constituent ratio of the 13 types of high-risk HPV showed no significant difference between 2013 and 2014 (Χ(2)=11.872, P=0.452). The 13 HPV genotypes detected, listed in a descending order of the constituent ratios, included HPV-52, -16, -58, -56, -39, -51, -68, -59, -31, -35, -18, -33 and -45 in 2013, and were HPV-52, -16, -58, -68, -18, -51, -56, -39, -31, -33, -59, -35 and-45 in 2014.
CONCLUSIONWe report a high prevalence of high-risk HPV among women in Guangzhou, which suggests the necessity of screening for high-risk HPV-DNA among women at all ages for prevention and early detection of cervical cancer.
