Preparation and characterization of Mn-Zn ferrite oxygene nanoparticle for tumor thermotherapy.
- Author:
Xiupeng JIA
1
;
Dongsheng ZHANG
;
Jie ZHENG
;
Ning GU
;
Weichang ZHU
;
Xiangshan FAN
;
Liqiang JIN
;
Meiling WAN
;
Qunhui LI
Author Information
1. School of Basic Medical Science, Southeast University, Nanjing 210009, China.
- Publication Type:Journal Article
- MeSH:
Electromagnetic Fields;
Ferric Compounds;
chemistry;
Humans;
Hyperthermia, Induced;
instrumentation;
Manganese Compounds;
chemistry;
Metal Nanoparticles;
chemistry;
Microscopy, Electron, Transmission;
Neoplasms;
therapy;
X-Ray Diffraction;
Zinc Compounds;
chemistry
- From:
Journal of Biomedical Engineering
2006;23(6):1263-1266
- CountryChina
- Language:Chinese
-
Abstract:
With the sulfate as the materials and NaOH as precipitator, Mn(0.4)Zn(0.6)Fe2O4 nanoparticles were produced, which are proved to be spinel Mn-Zn ferrite analyzed by X-ray diffraction(XRD). Their shapes are approximately global examined by transmission electron microscopy(TEM) and their average diameter is 50 nm measured with image analysis-system. The Curie temperature was measured and in vitro heating test in a alternating magnetic field was carried out. The results show that the Curie temperature is 105. 407 degrees C, While its magnetic fluid could rise to 43 degrees C - 47 degrees C due to different concentration in a alternating magnetic field. The result provide theoretical and practical evidence to select an appropriate material and concentration for tumor
