Association between ABO blood group and acute myocardial infarction
10.3760/cma.j.issn.0253-3758.2015.09.008
- VernacularTitle:ABO血型与急性心肌梗死的相关性分析
- Author:
Xiaoying HU
1
;
Shubin QIAO
;
Hong QIU
;
Shaodong YE
;
Lei FENG
;
Lei SONG
Author Information
1. 100037,中国医学科学院北京协和医学院国家心脏中心 阜外心血管病医院心内科
- Keywords:
Myocardial infarction;
ABO blood-group system
- From:
Chinese Journal of Cardiology
2015;43(9):785-787
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the association between the ABO blood group and the risk of myocardial infarction in Chinese people.Methods We retrospectively recruited 1 988 consecutive patients with acute myocardial infarction (AMI) and 1 856 non-coronary artery disease (non-CAD) subjects who hospitalized in our hospital between January 2013 and December 2013.The clinical features and ABO blood group were analyzed.Results Blood group distribution was A (27.1％,539/1 988),B (34.4％,684/1 988),AB(10.8％,215/1 988),O (27.7％,551/1 988) in patients with AMI and A (26.7％,496/1 856),B(32.2％,598/1 856),AB (10.8％,200/1 856),O (30.4％,564/1 856) in non-CAD group.The single factor analysis showed that blood group O tended to be more common in the non-CAD group than in AMI group (P =0.06).After adjustment for common cardiovascular risk factors such as age,gender,hypertension,diabetes,smoking and serum cholesterol level,the A,B,and AB blood groups were associated with increased risk of AMI compared with O blood group,and the difference was significant with A blood group (OR =1.229,95％ CI 1.019-1.482,P =0.031) and B blood groups (OR =1.214,95％ CI 1.017-1.449,P =0.032).In addition,non-O blood group remained significantly associated with the increased risk of AMI than O blood group after logistic regression analysis(OR =1.223,95％ CI 1.048-1.426,P =0.01).Conclusion Our results suggest that non-O blood group is associated with the increased risk of AMI.
