Value of evaluating diastolic function with the single-beat E/(e' × s) obtained by dual doppler echocardiograph in coronary heart disease patients with preserved left ventricular systolic function
10.3760/cma.j.issn.0253-3758.2014.04.009
- VernacularTitle:双脉冲多普勒超声心动图技术测量E/(e'×s)评价冠心病患者左心室舒张功能
- Author:
Jingjing WANG
1
;
Yundai CHEN
;
Jing WANG
;
Haipeng HUI
;
Guang ZHI
;
Yang MU
Author Information
1. 解放军总医院心血管内科
- Keywords:
Ventricular dysfunction,left;
Echocardiography;
Coronary disease
- From:
Chinese Journal of Cardiology
2014;42(4):305-308
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the value of E/(e' × s) in estimating left ventricular diastolic dysfunction in patients with coronary heart disease by dual Doppler echocardiograph.Methods Seventyseven consecutive coronary heart disease patients with preserved systolic function underwent echocardiographic study were included.The E,e'and s were obtained by the dual Doppler echocardiography and E/(e' × s),E/e' were calculated.All patients underwent left ventricular catheterization to measure left ventricular end diastolic pressure (LVEDP).The relationship between E/(e' × s),E/e' and LVEDP were analyzed.Patients were divided into normal diastolic function (LVEDP ＜ 12 mmHg,1 mmHg =0.133 kPa) and diastolic dysfunction group (LVEDP ≥ 12 mmHg).Results (1) Pearson correlation analysis showed that both E/(e' × s) and E/e' correlated well with LVEDP (r =0.68 and r =0.79,both P ＜ 0.01).(2) Using receiver operating characteristic analysis,the optimal cut-off for E/(e' × s) was 1.2 (sensitivity was 80％,specificity was 77％,AUC was 0.85) and for E/e' was 9.2 (sensitivity was 74％,specificity was 81％,AUC was 0.87) to predict left ventricular diastolic dysfunction.When combined cut-offs of E/(e' × s) ≥ 1.2 and E/e' ≥9.2,the sensitivity and specificity of predicting left ventricular diastolic dysfunction were 83％ and 71％ respectively,and AUC was 0.87.Conclusions E/(e' × s) can correctly reflect diastolic function status in patients with coronary artery disease.However,combined use of E/(e' × s)and E/e' does not add the prediction value on diastolic dysfunction in this patient cohort.
