Methodology overview of perfused rat intestine-liver preparation.
- Author:
Yiwei WANG
1
;
Rixin LIANG
;
Weipeng YANG
;
Yanli WANG
;
Xiaogang WENG
;
Qing YANG
;
Lan WANG
;
Xiaoxin ZHU
Author Information
1. Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Humans;
Intestinal Absorption;
Intestines;
chemistry;
physiology;
Liver;
chemistry;
physiology;
Models, Animal;
Perfusion;
methods;
Rats
- From:
China Journal of Chinese Materia Medica
2009;34(21):2701-2703
- CountryChina
- Language:Chinese
-
Abstract:
Since pang set up the perfused rat intestine-liver preparation and applied it to study the disposition of enalapril, this model has been widely considered to have the particularly advantage in studying the absorption, metabolism and first-pass effect. Now the methods and applications are to be reviewed and the perspective is to be discussed.
