Successful management of massive gastrointestinal bleeding using recombinant factor VIIa in an elderly patient with respiratory and renal failure.
- Author:
Minlong LIU
1
;
Guoen WANG
;
Qi MA
;
Junming REN
;
Lei GUO
;
Jun ZHANG
Author Information
1. Department of Intensive Care Medicine, Second Affiliated Hospital, Xi'an Jiaotong University College of Medicine, Xi'an 710004, China.E-mail: liuminlong2010@sina.cn.
- Publication Type:Case Reports
- MeSH:
Aged;
Factor VIIa;
therapeutic use;
Female;
Gastrointestinal Hemorrhage;
drug therapy;
Humans;
Recombinant Proteins;
therapeutic use;
Renal Insufficiency;
Respiratory Insufficiency
- From:
Journal of Southern Medical University
2014;34(8):1215-1216
- CountryChina
- Language:Chinese
-
Abstract:
Recombinant activated factor VII (rFVIIa) is a novel therapeutic agent for life-threatening massive gastrointestinal bleeding. We report a case of massive gastrointestinal bleeding in a 78-year-old female patient with respiratory and renal failure. After failure of management of the bleeding with routine pharmacotherapy, we gave the patient rFVIIa injection at the dose of 20 µg/kg and the bleeding was rapidly controlled. Adverse side effects of the drug were not observed in this patient.
