Clinical characteristics of abnormal savda syndrome type in human immunodeficiency virus infection and acquired immune deficiency syndrome patients: A cross-sectional investigation in Xinjiang, China.
- Author:
Mi-ji-ti PEIERDUN
1
;
Wen-xian LIU
2
;
Ai-ze-zi RENAGULI
2
;
Amat NURMUHAMMAT
2
;
Xiao-chun LI
3
;
Ka-ha-er GULIBAIER
3
;
Wu-la-mu AINIVAER
3
;
Upur HALMURAT
4
,
5
Author Information
- Publication Type:Journal Article
- Keywords: abnormal savda syndrome; depression; human immunodeficiency virus infection and acquired immune deficiency syndrome; symptoms; traditional Uighur medicine
- MeSH: Acquired Immunodeficiency Syndrome; diagnosis; Adult; CD4 Lymphocyte Count; China; ethnology; Cross-Sectional Studies; Female; HIV Infections; diagnosis; Humans; Male; Medicine, Traditional; Middle Aged; Surveys and Questionnaires
- From: Chinese journal of integrative medicine 2015;21(12):895-901
- CountryChina
- Language:English
-
Abstract:
OBJECTIVETo investigate the distribution of abnormal hilit syndromes in traditional Uighur medicine (TUM) among human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) patients, and to find out the clinical characteristics of abnormal savda syndrome type HIV/AIDS patients.
METHODSBetween June and July in 2012, 307 eligible HIV/AIDS patients from in-patient department and out-patient clinics of Xinjiang Uighur Autonomous Region the Sixth People's Hospital in Urumqi were investigated. TUM syndrome differentiation was performed by a senior TUM physician. Each participant completed a Sign and Symptom Check-List for Persons Living with HIV/AIDS (SSC-HIV) questionnaire. Depression was evaluated by using Hamilton Rating Scale for Depression Questionnaire. Blood specimen was collected from each participant to test the levels of blood chemicals.
RESULTSOf 307 HIV/AIDS patients, 189 (61.6%) were abnormal savda syndrome type, 118 (38.4%) were non-abnormal-savda syndrome type. Mean CD4 counts of abnormal savda syndrome type patients was (227.61±192.93) cells/µL, and the prevalence of anemia, thrombocytopenia, and elevated cystatin C were 49.7%, 28.6%, and 44.7%, which were significantly higher than those in the non-abnormal-savda syndrome type patients (26.3%, 16.0% and 25.0%,P<0.05). In addition, depression (79.9%) and HIV/AIDS-related symptoms such as fatigue (42.3%), back aches (40.7%), lack of appetite (33.9%), night sweats (31.7%) were more common among abnormal savda syndrome patients (P<0.05).
CONCLUSIONAbnormal savda syndrome is the dominant syndrome among HIV/AIDS patients, and they present a more sever clinical manifestation.
