CT coronary angiography combined with adenosine stress myocardial perfusion scintigraphy for detecting flow-limiting coronary stenoses.
- Author:
Qi WANG
1
,
2
;
Jing QIN
;
Zhi-guo WANG
;
Zhi-wei GUAN
;
Wei DONG
;
Zhi-jun SUN
;
Lu-yue GAI
;
Yun-dai CHEN
;
Jia-He TIAN
;
Li YANG
Author Information
- Publication Type:Journal Article
- MeSH: Adenosine; Aged; Coronary Angiography; methods; Coronary Stenosis; diagnosis; diagnostic imaging; Female; Humans; Male; Middle Aged; Myocardial Perfusion Imaging; methods; Tomography, Emission-Computed, Single-Photon; methods; Tomography, X-Ray Computed
- From: Journal of Southern Medical University 2011;31(2):210-215
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo assess the feasibility and accuracy of CT coronary angiography (CTCA) combined with adenosine stress myocardial perfusion scintigraphy (MPS) for diagnosis of flow-limiting coronary stenosis.
METHODSA total of 105 patients with suspected or established coronary artery disease (CAD) underwent CTCA and MPS within 4 weeks before invasive coronary angiography. The accuracy of CTCA/MPS in the diagnosis of flow-limiting coronary stenosis was evaluated in comparison with the results of quantitative coronary angiography and MPS.
RESULTSThe sensitivity, specificity, positive predictive value and negative predictive value of CTCA/MPS as a combined approach for detection of flow-limiting coronary stenosis were all 100%. In 16% (9/55) of the patients, revascularization procedures were performed and no flow-limiting stenosis was found.
CONCLUSIONCombination of CTCA and MPS has an excellent accuracy for detecting flow-limiting coronary stenosis as compared with quantitative coronary angiography/MPI, and can be a useful gatekeeper for revascularization procedures.
