Studies on chemical constituents of Isodon excisoides.

Author: Li-Ping DAI ¹ ; Meng ZHAO ¹ ; Chun LI ² ; Jiao-Jiao ZHAO ¹ ; Ling-Xia ZHANG ¹ ; Sui-Qing CHEN ¹ ; Hui-Min GAO ² ; Zhi-Min WANG ²
Author Information

1. School of Pharmacy, Henan University of Traditional Chinese Medicine, Zhengzhou 450046, China.
2. Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Publication Type:Journal Article
Keywords: 3-O-β-D-allopyranosyl-1-octen-3-ol; Isodon excisoides; blumenol A; lumichrome
From: China Journal of Chinese Materia Medica 2016;41(18):3361-3365
CountryChina
Language:Chinese
Abstract: The chemical constituents of the water extraction of the aerial parts of Isodon excisoides were investigated by various chromatographic methods including D-101 macroporous adsorptive resins, silica gel, Sephadex LH-20, MCI and semi-preparative HPLC. As a result, six compounds were separated and purified.By analyses of the HR-ESI-MS, 1D and 2D NMR spectra, their structures were determined as 3-O-β-D-allopyranosyl-1-octen-3-ol(1), blumenolA (2), lumichrome (3), loliolide(4), cirsiliol(5) and pedalitin(6). Compound 1 was a new compound, and compounds 2-4 were isolated from this plant for the first time.