The high risk factors of allergen sensitization among 518 children with allergic rhinitis symptoms
10.3760/cma.j.issn.1673-0860.2014.04.004
- VernacularTitle:具有变应性鼻炎症状的518例儿童变应原致敏性高危因素分析
- Author:
Weili DAI
1
;
Wentong GE
;
Jie ZHANG
;
Yamei ZHANG
Author Information
1. 100045,首都医科大学附属北京儿童医院耳鼻咽喉头颈外科 北京市儿科研究所儿童耳鼻咽喉头颈外科疾病北京市重点实验室
- Keywords:
Child;
Rhinitis,allergic,perennial;
Anaphylaxis;
Risk factors
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2014;49(4):277-282
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the high risk factors of allergen sensitization among 1-16 years old children with allergic rhinitis (AR) symptoms.Methods Medical history was collected from 518 children with AR symptoms aged 1 to 16 years old between April 2011 and November 2012,including five aspects:basic information,disease characteristics,associated with other allergic diseases,growth and development history and genetic history and so on.The allergens were determined by UniCAP 100 system.The high risk factors of allergen sensitization(sIgE ≥ grade Ⅲ) among 1-16 years old children with AR symptoms were analyzed.The data processing and statistical analysis were conducted by SPSS 17.0 software.Results Three hundred and thirty of 518 patients (63.7％) could be diagnosed as AR.The primary allergen was mixed fungal(52.4％).The highest percentage of allergen sIgE ≥ grade Ⅲ accounted for the corresponding allergen positive cases was 71.1％ (mixed fungal).Single factor analysis of clinical characteristics in the groups of AR and non AR showed that the history of months (x2 =-3.591),concomitant allergic conjunctivitis (x2 =12.325) and cats or dogs at home (x2 =5.615) were statistically significant between the two groups(all P ＜ 0.05).In children with AR,single factor analysis of clinical characteristics in the groups of whether positive allergen level ≥ grade Ⅲ showed that the concomitant asthma (x2 =4.097),breastfeeding(x2 =4.186),the housing situation (x2 =4.360) and the bedroom toward (x2 =4.656) were statistically significant between the two groups (all P ＜ 0.05).In children with AR,single factor analysis of clinical characteristics in different age groups showed that the history of months(x2 =64.999),concomitant eczema (x2 =24.056),concomitant insect bite dermatitis (x2 =9.148),cats or dogs at home (x2 =8.529) and mother suffered from AR (x2 =9.565) were statistically significant in different age groups (all P ＜ 0.05).Conclusion The study revealed that the longer of history,concomitant allergic conjunctivitis and cats or dogs at home are risk factors for AR;In children with AR,not breastfeeding and the bedroom toward back are risk factors for inhalation allergen sIgE ≥ grade Ⅲ.
