Structure identification of two new cerebrosides from Helicia nilagirica Beed.
- Author:
Tong WU
1
;
De-Yun KONG
;
Hui-Ting LI
Author Information
- Publication Type:Journal Article
- MeSH: Cerebrosides; chemistry; isolation & purification; Glucosylceramides; chemistry; isolation & purification; Molecular Conformation; Molecular Structure; Plant Leaves; chemistry; Plants, Medicinal; chemistry; Proteaceae; chemistry
- From: Acta Pharmaceutica Sinica 2004;39(7):525-527
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo study the bioactive components from Helicia nilagirica.
METHODSCompounds were separated with a combination of multi-chromatography. Their chemical structures were determined on the basis of spectral analysis and chemical evidence.
RESULTSTwo compounds were isolated from the leaves of Helicia nilagirica. Compound 1 was elucidated as 1-O-3-D-glucopyranosyl-(2S,3S,4R,8Z)-2-[(2'R)-2'-hyd roxylignocenoyl-amino]-8-octadecene-1, 3, 4-triol. Compound 2 was an analogue of 1.
CONCLUSIONThe two compounds are new cerebrosides.
