Advances in Research and Application of Liquid Biopsy in Lymphoma-Review.
10.7534/j.issn.1009-2137.2017.04.054
- VernacularTitle:液体活检在淋巴瘤中的研究和应用进展
- Author:
Yang ZHANG
1
;
Hong-Xing LIU
2
Author Information
1. Department of Pathology and Medical Laboratorial Examination, Hebei Yanda LU Dao-Pei Hospital, Langfang 065201, Hebei Province, China.
2. Department of Pathology and Medical Laboratorial Examination, Hebei Yanda LU Dao-Pei Hospital, Langfang 065201, Hebei Province, China. E-mail: lhongxing@outlook.com.
- Publication Type:Journal Article
- From:
Journal of Experimental Hematology
2017;25(4):1259-1262
- CountryChina
- Language:Chinese
-
Abstract:
Liquid biopsy as a new rising non-invasive testing method play an important role in assisting diagnosis, evaluating efficacy and prognosis, monitoring early recurrence and drug resistance. It has been widely applied in some types of solid tumors. Lymphoma is a group of heterogeneous hematological malignancies, among which most subtypes without specific tumor markers, and the evaluation of the efficacy and prognosis mainly depend on biopsy and imaging. Compared with other solid tumors, lymphoma cells were characterized by a trend to enter in peripheral circulation, and the diversity of immunoglobulin molecules can be monitored as marker, which can be applicable to liquid biopsy. With the advances in detection technology, research and application of liquid biopsy in lymphoma have attracted more attentions. In this review, the concept of liquid biopsy, base for liquid biopsy and its current situation of performance, progress of research and performace of liquid biopsy in lymphoma and so on are summarized.
