Increased Expression and Activity of MMP-9 in C-reactive Protein- induced Human THP-1 Mononuclear Cells Is Related to Activation of Nuclear Factor Kappa-B
10.1007/s11596-009-0401-0
- Author:
SHENG FUQIANG
1
;
CHENG LONGXIAN
;
ZENG QIUTANG
;
GAO WEN
Author Information
1. Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China;Department of Cardiology, Affiliated Taihe Hospital, Yunyang Medical College, Shiyan 442000, China
- Keywords:
C-reactive protein;
human THP-1 mononuclear cell;
matrix metalloproteinase-9;
nuclear factor kappa-B
- From:
Journal of Huazhong University of Science and Technology (Medical Sciences)
2009;29(4):399-403
- CountryChina
- Language:Chinese
-
Abstract:
n of NF-κ3. Down-regulation of the expression and activity of MMP-9 may be a new treatment alternative for plaque stabilization by inhibiting the NF-κB activation.
