Advances in genetic research of congenital hypothyroidism in China.
- Author:
Xiao-Yu CHEN
1
;
Xiao-Song QIN
Author Information
1. Clinical Laboratory, Shengjing Hospital of China Medical University, Shenyang 110004, China. 957509010@qq.com.
- Publication Type:Journal Article
- MeSH:
Congenital Hypothyroidism;
genetics;
Humans;
Iodide Peroxidase;
genetics;
Membrane Proteins;
genetics;
PAX8 Transcription Factor;
genetics;
Receptors, Thyrotropin;
genetics;
Thyroglobulin;
genetics;
Transcription Factors;
genetics
- From:
Chinese Journal of Contemporary Pediatrics
2018;20(3):243-250
- CountryChina
- Language:Chinese
-
Abstract:
Congenital hypothyroidism (CH), which results from insufficient thyroid hormone biosynthesis, is one of the most common neonatal endocrine disorders. Thyroid dysgenesis and thyroid dyshormonogenesis are the two causes of CH and either one will lead to deficiencies of enzymes during thyroid hormone biosynthesis and insufficient thyroid hormone biosynthesis. Recently, researchers have performed extensive studies on genetics of CH. This paper reviews genes reported to be associated with CH in China.
