Left ventricular dyssynchrony evaluated by echocardiography in chronic heart failure patients with normal and wide QRS duration
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3321/j.issn:0253-3758.2008.01.011
   		
        
        	
        		- VernacularTitle:心电图QRS间期与慢性心力衰竭左心室同步性关系的超声评价
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yin-Guang SUN
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Wei-Feng SHEN
			        		
			        		;
		        		
		        		
		        		
			        		Feng-Ru ZHANG
			        		
			        		;
		        		
		        		
		        		
			        		Yi-Qiong XU
			        		
			        		;
		        		
		        		
		        		
			        		Wen RUAN
			        		
			        		;
		        		
		        		
		        		
			        		Qin-Hua ZHAO
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 上海交通大学医学院附属瑞金医院
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Heart failure,congestive;
			        		
			        		
			        		
				        		Echocardiography,Doppler;
			        		
			        		
			        		
				        		Electrocardiography
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Cardiology
	            		
	            		 2008;36(1):44-48
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective The aim of the study is to evaluate the left ventricular(LV)dyssynchrony in chronic heart failure(HF)Patients with normal and wide QRS duration.Methods Time to peak velocity at peak systolic and early diastolic phase(Ts and Te)were determined in 12 segments of LV by echocardiography(GE Vivid 7)in 54 HF patients(28 with wide and 26 with normal QRS duration)and 15 normal controls to evaluate LV systolic and diastolic dyssynchrony.The risk factors related to LV dyssynchrony were also evaluated.Results LV end systolic and diastolic volumes were significantly larger and 12 segmental mean Ts and maximal Te difference(Te-diff)were significantly higher in HF patients with wide QRS duration tllan HF patients with normal QRS duration.Using mean Ts≥182 ms as the cut-off value,systolic dyssynchrony was present in 46% HF patients with normal QRS and 71% HF patients with wide QRS.Using Te-diff≥79 ms as the cut-off value,diastolic dyssynehrony was seen in 58% HF patients with normal QRS and 89% HF patients with wide QRS.Combined systolic and diastolic dyssynchrony was seen in 31% HF patients with normal QRS and in 64% HF patients with wide QRS.Systolic dyssynchrony Was significantly correlated to LV end systolic volume and diastolic dyssynchrony was correlated to end diastolic volume.Conclusion Percentage of LV dyssyncrony was significantly higher in HF patients with wide QRS,especially in HF patients with increased LV end systolic and diastolic volume.