Is Brain Biopsy Rational in Shunt Operation of Normal Pressure Hydrocephalus in Elderly?.
- Author:
Yong JEONG
1
;
Ju Hee CHIN
;
Jay C KWON
;
Yeon Lim SUH
;
Jung Mi PARK
;
Sang Eun KIM
;
Duk L NA
Author Information
1. Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Korea. dukna@smc.samsung.co.kr
- Publication Type:Case Report
- Keywords:
Normal pressure hydrocephalus;
Alzheimer's disease;
Brain biopsy
- MeSH:
Aged*;
Alzheimer Disease;
Biopsy*;
Brain*;
Female;
Follow-Up Studies;
Humans;
Hydrocephalus;
Hydrocephalus, Normal Pressure*
- From:Journal of the Korean Neurological Association
2001;19(6):654-659
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Early detection of AD in its initial or preclinical stage has become increasingly important. We report a 73-year-old woman who was confirmed to have AD by a cortical biopsy performed concomitantly during a shunt operation for hydrocephalus. The triads of hydrocephalus improved after the operation, as did follow-up neuropsychological and FDG-PET findings. However, 2.5 years after the operation, the patient developed cognitive declines with abnormal behaviors, which was considered to be an evolved form of AD from the preclinical stage.
