Diagnostic Value of (18)F-FDG-PET/CT for Multiple Myeloma.
- Author:
Jian-Qiu LI
1
;
Li-Li GUAN
1
;
Jie WANG
1
;
Zhi-Xiang LV
1
;
Yue-Hong XU
1
;
Hua PANG
2
,
3
Author Information
- Publication Type:Journal Article
- MeSH: Fluorodeoxyglucose F18; Humans; Multimodal Imaging; Multiple Myeloma; Positron-Emission Tomography; Tomography, X-Ray Computed
- From: Journal of Experimental Hematology 2015;23(4):1049-1052
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the diagnostic value of (18)F-FDG-PET/CT in multiple myeloma (MM).
METHODSA total of 66 patients, who were highly suspected of MM in our hospital from July 2012 to December 2014, were chosen as study objects. All patients were diagnosed or excluded by pathological examination. All patients were detected by (18)F-FDG-PET/CT, and its diagnostic value was analyzed. The number of focuses were counted.
RESULTSOut of 66 patients 59 patients (89.39%) were diagnosed with multiple myeloma. The sensitivity of PET was 98.31%, the specificity of PET was 85.71%, the Youden index was 0.8402; the sensitivity of CT was 96.61%, the specificity of CT was 85.71%, the Youden index was 0.8232; the sensitivity of PET/CT was 100.00%, the specificity of PET/CT was 83.33%, the Youden index was 0.8333. In 59 MM patients, 635 focuses were detected, out of them 572 focuses (90.08%) were detected by CT, 593 focuses (93.39%) were detected by PET, 530 focuses (83.46%) were coincided on PET/CT.
CONCLUSION(18)F-FDG-PET/CT has diagnostic value for multiple myeloma, and it can be used in locating and counting focuses, as well as in evaluating the treatment efficacy and guiding the clinical work.
