Small-dose vardenafil restores erectile function after penile surgery.
- Author:
Geng-Sheng ZHANG
1
;
Juan ZHOU
;
Qi CHEN
;
Jun DA
;
Guo-Qin DONG
;
Yue-Qing JIANG
;
Zhong WANG
;
Zhi-Kang CAI
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Erectile Dysfunction; drug therapy; Humans; Imidazoles; administration & dosage; therapeutic use; Male; Middle Aged; Penile Erection; Penis; surgery; Piperazines; administration & dosage; therapeutic use; Postoperative Period; Recovery of Function; Sulfones; administration & dosage; therapeutic use; Treatment Outcome; Triazines; administration & dosage; therapeutic use; Vardenafil Dihydrochloride; Vasodilator Agents; administration & dosage; therapeutic use
- From: National Journal of Andrology 2011;17(4):322-324
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the impact of penile surgery on the erectile function of the patient and to evaluate the role of small-dose vardenafil in restoring the impaired penile erection.
METHODSSixty cases of penile cavernosum surgery were equally and randomly divided into a vardenafil and a control group, the former treated 5 - 7 days after surgery with 10 mg vardenafil every other day, while the latter given vitamin E at 100 mg once a day, both for 12 weeks. The penile erectile function of the patients was evaluated with the IIEF-5 questionnaire before surgery and at 3 and 6 months after vardenafil medication.
RESULTSThe mean IIEF-5 scores of the vardenafil group were 18.83 +/- 2.98 and 20.13 +/- 2.98 at 3 and 6 months after vardenafil medication, significantly higher than 14.21 +/- 3.62 before surgery (P > 0.05), while that of the control group was significantly decreased at 3 months as compared with the preoperative score (13.38 +/- 2.82 versus 15.80 +/- 3.02, P < 0.05). The vardenafil group showed the highest IIEF-5 score after surgery (P < 0.05).
CONCLUSIONLong-term administration of small-dose vardenafil after penile surgery helps to restore and maintain penile erectile function.
