Pathological changes in the sinoatrial node tissues of rats caused by pulsed microwave exposure.

Author: Yan Qing LIU ¹ ; Ya Bing GAO ² ; Ji DONG ² ; Bin Wei YAO ² ; Li ZHAO ² ; Rui Yun PENG ²
Author Information

1. Department of Experimental Pathology, Beijing Institute of Radiation Medicine, Beijing 100850, China; The Affiliated Hospital of Logistic College of Chinese People's Armed Police Forces, Tianjin 300162, China.
2. Department of Experimental Pathology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Publication Type:Letter
MeSH: Animals; Extracellular Matrix; pathology; radiation effects; Male; Microwaves; adverse effects; Rats; Rats, Wistar; Sinoatrial Node; pathology; radiation effects
From: Biomedical and Environmental Sciences 2015;28(1):72-75
CountryChina
Language:English
Abstract: To observe microwave induced dynamic pathological changes in the sinus nodes, wistar rats were exposed to 0, 5, 10, 50 mW/cm2 microwave. In 10 and 50 mW/cm2 groups, disorganized sinoatrial node cells, cell swelling, cytoplasmic condensation, nuclear pyknosis, and anachromasis, swollen, and empty mitochondria, and blurred and focally dissolved myofibrils could be detected from 1 to 28 d, while reduced parenchymal cells, increased collagen fibers, and extracellular matrix remodeling of interstitial cells were observed from 6 to 12 months. In conclusion, 10 and 50 mW/cm2 microwave could cause structural damages in the sinoatrial node and extracellular matrix remodeling in rats.