Creation and anti-cancer potency in HeLa cells of a novel chimeric toxin, HMGNCIDIN, composed of HMGN2 a-helical domain and PE38 KDEL domain III.
- Author:
Wen-bi XIONG
1
;
Ning HUANG
;
Yun FENG
;
Qi WU
;
Bo-yao WANG
Author Information
1. Department of Pharmacology, West China Medical Center, Sichuan University, Chengdu, Sichuan 610041, China.
- Publication Type:Journal Article
- MeSH:
ADP Ribose Transferases;
chemistry;
pharmacology;
Animals;
Antineoplastic Agents;
pharmacology;
Bacterial Toxins;
chemistry;
pharmacology;
Exotoxins;
chemistry;
pharmacology;
Female;
HMGN2 Protein;
chemistry;
pharmacology;
HeLa Cells;
Humans;
Immunotoxins;
pharmacology;
Mice;
Mice, Inbred BALB C;
Protein Structure, Tertiary;
Recombinant Fusion Proteins;
biosynthesis;
pharmacology;
Virulence Factors;
chemistry;
pharmacology
- From:
Chinese Medical Journal
2008;121(1):82-85
- CountryChina
- Language:English
